200816-49-5Relevant academic research and scientific papers
Synthesis of new spiro heterocyclic compounds derived from rhodanine derivatives
Ghany, H. Abdel
, p. 173 - 180 (1997)
5,5-Dibromo-3-phenyl-2-thioxo-4-thiazolidinone 2, was reacted with bidentates, or with CS2 and active methylenes under PTC conditions to afford the corresponding spiro compounds 4a-h or 5a-e. 5-ethoxymethylene-3-phenyl-2-thioxo-4-thiazolidinone 3 was treated with diamino or aminomercaplo compounds to give the desired products 6a-d. Treatment of compound 3 with malononitrile gave compound 7. Reaction of compound 7 with some active methylenes affords the corresponding spiro cyclopentenes 8a-c.
