20097-40-9

Upstream product

• 488-54-0 neo-inositol 
• 108-24-7 acetic anhydride 
• 17793-95-2 (1RS,2RS)-cyclohexa-3,5-diene-1,2-diol 
• 64288-00-2 trans-cyclohexa-3,5-diene-1,2-diyl diacetate 
• 188839-30-7 (3aS,4R,5R,6R,7R,7aS)-4,7-Bis-(tert-butyl-diphenyl-silanyloxy)-2,2-dimethyl-hexahydro-benzo[1,3]dioxole-5,6-diol 
• 110-86-1 pyridine 
• 6090-95-5 (+/-)-1,2-anhydro-allo-inositol 
• 4381-96-8 (+/-)-tetraacetylconduritol C 
• 7487-88-9 magnesium sulfate 
• 18685-70-6 chiro-inositol 
• 76235-11-5 deseryladenomycin 
• 64-17-5 ethanol 
• 4381-96-8 (+/-)-tetra-O-acetylconduritol F 
• 594858-53-4 4,5-didesoxy-4,5-dibromo-1,2,3,6-tetra-O-acetyl-D-myo-inositol 

Downstream Products

• 488-54-0 neo-inositol 

Relevant academic research and scientific papers

A short and efficient route from myo - To neo -inositol

An efficient route from myo- to neo-inositol is described. The key steps of the sequence are oxidation of the hydroxy group at C-5 to the corresponding ketone, followed by a highly (dr = 7.8:1) stereoselective reduction. The route includes nine steps with an overall yield of 51% and is therefore superior to all hitherto reported methods for the preparation of neo-inositol. Georg Thieme Verlag Stuttgart New York.

Stereoselective synthesis of myo-, neo-, L-chiro, D-chiro, allo-, scyllo-, and epi-inositol systems via conduritols prepared from p-benzoquinone

A practical route is described for the flexible preparation of a wide variety of inositol stereoisomers and their polyphosphates. The potential of this approach is demonstrated by the synthesis of myo-, L-chiro-, D-chiro-, epi-, scyllo-, allo-, and neo-inositol systems. Optically pure compounds in either enantiomeric form can be prepared from p-benzoquinone via enzymatic resolution of a derived conduritol B key intermediate. High-performance anion-exchange chromatography with pulsed amperometric detection permits inositol stereoisomers to be resolved and detected with high sensitivity. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.

Catalytic One-Pot Osmylation of Cyclohexadienes: Stereochemical and Conformational Studies of the Resulting Polyols

Catalytic double osmylation is described for a series of cyclohexadienes in acetone/H2O in the presence of the co-oxidant N-methylmorpholine N-oxide (NMO).The formation of polyols occurred stereospecifically with cyclohexadienes 3, 7, and 11a, leading thereby to tetrols 5a, and 9a and to allo-inositol (14a), respectively.To the contrary, trans-cyclohexadiene-diol 15a gave a mixture of the stereoisomeric inositols 18a (epi), 19a (neo), and 20a (chiro).High-field NMR let to clearcut conformational analyses of the polyhydroxylated derivatives.