201049-33-4Relevant academic research and scientific papers
Synthesis and biological evaluation of flavan-3-ol derivatives as positive modulators of GABAA receptors
Mewett, Kenneth N.,Fernandez, Sebastian P.,Pasricha, Anmol K.,Pong, Alice,Devenish, Steven O.,Hibbs, David E.,Chebib, Mary,Johnston, Graham A.R.,Hanrahan, Jane R.
experimental part, p. 7156 - 7173 (2010/03/04)
We herein describe the synthesis and positive modulatory activities of a small library of flavan-3-ol derivatives on α1β2γ2L GABAA receptors. Structure-activity relationships of various substituents on the A, B
Enantioselective synthesis of flavonoids. Part 3. trans- and cis-flavan-3-ol methyl ether acetates
Van Rensburg, Hendrik,Van Heerden, Pieter S.,Ferreira, Daneel
, p. 3415 - 3421 (2007/10/03)
Asymmetric dihydroxylation of a series of polyoxygenated 1,3-diarylpropenes with AD-mix-α or AD-mix-β in the presence of methanesulfonamide and subsequent acid-catalysed cyclization, affords for the first time synthetic access to trans- and cis-flavan-3-ol derivatives, essentially enantiopure and in good yield.
