201049-99-2Relevant academic research and scientific papers
On the reaction of 2-phenylaminothiazoline with α-halogenoketones
Demchenko,Chumakov,Krasovskii,Pirozhenko,Lozinskii
, p. 724 - 727 (1997)
It was established that the alkylation of 2-phenylaminothiazoline with substituted phenacyl bromides proceeds at the exocyclic nitrogen atom with the formation of 5-aryl-7-phenyl-2,3-dihydroimidazo[2,1-b]thiazolium bromides. In order to confirm the struct
Synthesis, antibacterial activity and binding mode analysis of some novel 1,4-diaryl imidazole thiones
Ganguly, Swastika,Singh, Nalini,Upadhyay, Arpita
, p. 419 - 424 (2019/01/21)
A novel series of fifteen diaryl imidazole thiones 2a-o was synthesized by reacting the corresponding 1-(aryl)-2-(arylamino)-ethanones 1 with ammonium thiocyanate. The compounds have been characterized on the basis of elemental analysis and spectral data.
T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES
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Page/Page column 30; 31, (2008/12/07)
The present invention relates to compounds of formula IA or IB. The present invention also concerned to a method of treating immunologic diseases or pathological conditions in association with T cell involving an immunologic component using T-cell inhibitors, optionally in combination with one or more other drugs selected from steroids, DMARDs, NSAIDs, immunosuppressive, and biological modifiers, pharmaceutical compositions comprising said compounds of formula IA or IB together with said other drugs, and the use of T-cell inhibitors for the manufacture of a pharmaceutical composition for the treatment of immunologic diseases or pathological conditions involving an immunologic component.
