201055-38-1Relevant academic research and scientific papers
Synthesis of chiral allyltitaniums having an amino group at the C-4 position and their diastereoselective addition reaction with aldehydes
Teng, Xin,Kasatkin, Aleksandr,Kawanaka, Yasufumi,Okamoto, Sentaro,Sato, Fumie
, p. 8977 - 8980 (2007/10/03)
Chiral allyltitaniums having an amino substituent at the C-4 position are prepared from optically active allylic alcohol derivatives 1 and Ti(O-i-Pr)4/2i-PrMgCl reagent, which, in turn, react with aldehydes regio- and stereoselectively to afford 3-amino-2-vinylalkanols in excellent yields.
