201135-18-4Relevant academic research and scientific papers
Toward a transition state analog inhibitor of N-acetylglucosaminyl transferase V
Kaneko, Mitsuaki,Kanie, Osamu,Kajimoto, Tetsuya,Wong, Chi-Huey
, p. 2809 - 2812 (2007/10/03)
The tumor related enzyme N-acetylglucosaminyltransferase V catalyzes the transfer of GlcNAc to OH-6 of branching Man to give complex oligosaccharide structures. A transition state analog inhibitor of this enzyme was designed and a model compound was synthesized to illustrate the feasibility of the synthetic strategy.
