201142-52-1

Upstream product

• 545-06-2 trichloroacetonitrile 
• 824-94-2 p-methoxybenzyl chloride 
• 193359-93-2 (3aR,6R,7S,7aS)-2,2-Dimethyl-6-phenylsulfanyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-7-ol 
• 201142-50-9 (2R,3S,4S,5R)-4,5-Bis-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-2-phenylsulfanyl-tetrahydro-pyran 
• 201142-47-4 (3aR,6R,7S,7aR)-7-(4-Methoxy-benzyloxy)-2,2-dimethyl-6-phenylsulfanyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran 
• 201142-49-6 (3R,4R,5S,6R)-5-(4-Methoxy-benzyloxy)-6-phenylsulfanyl-tetrahydro-pyran-3,4-diol 
• 69739-34-0 t-butyldimethylsiyl triflate 

Downstream Products

• 213824-35-2 C₅₇H₁₀₀O₉Si₄ 
• 201142-56-5 C₅₇H₁₀₀O₉Si₄ 
• 201142-55-4 C₅₇H₁₀₂O₉Si₄ 
• 174545-76-7 eleutherobin 
• 201142-53-2 (Z)-2-[(2R,3S,4S,5R)-4,5-Bis-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-tetrahydro-pyran-2-yloxymethyl]-3-[(1S,2R,6R)-6-isopropyl-3-methyl-2-((2S,3S)-3-methyl-2,3-bis-triethylsilanyloxy-pent-4-ynyl)-cyclohex-3-enyl]-propenal 
• 201142-54-3 (Z)-2-[(2S,3S,4S,5R)-4,5-Bis-(tert-butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-tetrahydro-pyran-2-yloxymethyl]-3-[(1S,2R,6R)-6-isopropyl-3-methyl-2-((2S,3S)-3-methyl-2,3-bis-triethylsilanyloxy-pent-4-ynyl)-cyclohex-3-enyl]-propenal 

Relevant academic research and scientific papers

Total synthesis of eleutherobin and eleuthosides A and B

The total synthesis of the cytotoxic marine natural products eleutherobin (1) and eleuthosides A (2) and B (3) is described. The strategy involves glycosidation of the (+)-carvone-derived intermediate 7 with the arabinose-derived trichloroacetimidate 9 fo