201151-00-0

Upstream product

• 205485-25-2 2-methoxy-4-<3-trifluoromethyl-3H-diazirin-3-yl>benzaldehyde 
• 205485-24-1 3-(3-methoxyphenyl)-3-(trifluoromethyl)-3H-diazirine 

Downstream Products

• 173949-59-2 2-methoxy-4-(3-trifluoromethyl-3H-diazirin-3-yl)-benzoic acid 2,5-dioxopyrrolidin-1-yl ester 
• 679406-27-0 N-(2-amino-ethyl)-2-methoxy-4-(3-trifluoromethyl-3H-diazirin-3-yl)-benzamide 
• 679406-28-1 C₁₉H₂₄F₃N₅O₆ 
• 679406-23-6 C₅₅H₈₀F₃N₅O₁₆ 
• 679406-24-7 C₅₅H₈₀F₃N₅O₁₆ 

Relevant academic research and scientific papers

Synthesis of photoaffinity probes of tautomycin

Two types of photoaffinity probe, which possesses a benzophenone or a diazirine photophore on the 2-position of tautomycin, were prepared in order to prove the details of binding site to PP1. These photoaffinity probes were designed on the basis of the structure-activity relationship; thus, the diacid moiety is indispensable. The selective introduction of photolabeling units on the 2-position of tautomycin was achieved through the 2-oxime of tautomycin diacid.

A versatile approach for functionalization of 3-aryl-3-trifluoromethyldiazirine photophor

We introduce here a novel and simple method for the carbonylation of (alkoxyphenyl)diazirine. 3-(3-Methoxyphenyl)-3-trifluoromethyldiazirine was found to be stable under a typical Friedel-Crafts reaction producing carboxaldehyde derivatives of methoxyphen