20120-08-5

Basic information

• Product Name: 3β-hydroxyandrostan-17-one
• Synonyms: 3β-hydroxyandrostan-17-one
• CAS NO: 20120-08-5
• Molecular Weight: 290.446
• Mol File: 20120-08-5.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 3β-hydroxyandrostan-17-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3β-hydroxyandrostan-17-one(20120-08-5)
• EPA Substance Registry System: 3β-hydroxyandrostan-17-one(20120-08-5)

Safety Data

• Hazardous Substances Data: 20120-08-5(Hazardous Substances Data)

Upstream product

• 19325-01-0 C₂₁H₃₄OS₂ 
• 1192475-82-3 androstendione 
• 53-43-0 dehydroepiandrosterone 
• 571-20-0 (5α)-androstane-3β,17β-diol 
• 571-20-0 (3S,5S,10S,13S)-10,13-Dimethyl-hexadecahydro-cyclopenta[a]phenanthrene-3,17-diol 
• 57711-44-1 Androsterone-dimethyl-tert.-butylsilyl-ether 

Downstream Products

• 571-20-0 (5α)-androstane-3β,17β-diol 
• 1382475-29-7 C₂₄H₃₃NO 
• 154229-26-2 17-(pyridin-3-yl)androst-16-en-3-one 
• 846-46-8 androstanedione 
• 1239-31-2 3β-acetoxy-5α-androstan-17-one 
• 846-46-8 androstanedione 

Relevant articles and documents

Catalytic removal of tert-butyldimethylsilyl (TBS) ether by PVP-I

A mild, efficient and rapid protocol the deprotection of alcoholic TBDMS ethers using PVP-1 as catalyst in methanol, the procedure of deprotection of various TBDMS ethers were found to be very convenient, easy work-up, high yielding.

Potential of Azadirachta indica cell suspension culture to produce biologically active metabolites of dehydroepiandrosterone

Dehydroepiandrosterone (1) was investigated for biotransformation studies using the plant cell suspension culture of Azadirachta indica A. Juss. for the first time, yielding metabolites 2-6: 5α,3,17-androstanedione (2), 5-androstene-3β,17β-diol (3), 3β-hydroxyandrostan-17-one (4), 3β,11α-dihydroxy-5-androsten-17-one (5), and 3β,7α- dihydroxy-5-androsten-17-one (6), whose structures were solved through modern spectroscopic methods. All five compounds 2-6 have not been reported obtained by this way before. This is a new method to biosynthesize compounds 2-6 employing cultured cells of A. indica. Metabolites 2, 3, and 6 are important biologically active compounds, whereas 4 is a precursor for the production of the 7-hydroxylated compound having antiglucocorticoid and neuroprotective effects.

A New Procedure for Dethioacetalization via Equilibrium Exchange with Aqueous Acetone, Paraformaldehyde and Amberlyst 15 as Acidic Catalyst

Carbonyl compounds were regenerated from corresponding Ethanediyl S,S-Acetals via equilibrium exchange with aqueous acetone, paraformaldehyde and Amberlyst 15, as acidic catalyst, at 80 deg C.