20123-60-8

Upstream product

• 106-96-7 propargyl bromide 
• 2050-16-0 4,4'-dihydroxyazobenzene 
• 108-95-2 phenol 
• 123-30-8 4-amino-phenol 

Downstream Products

• 20348-00-9 4,4'-[4,4'-(4,4'-diazenediyl-diphenoxy)-di-but-2-ynyl]-bis-morpholine 

Relevant academic research and scientific papers

A Light-Operated Molecular Cable Car for Gated Ion Transport

Inspired by the nontrivial and controlled movements of molecular machines, we report an azobenzene-based molecular shuttle PR2, which can perform light-gated ion transport across lipid membranes. The amphiphilicity and membrane-spanning molecular length enable PR2 to insert into the bilayer membrane and efficiently transport K+ (EC50=4.1 μm) through the thermally driven stochastic shuttle motion of the crown ether ring along the axle. The significant difference in shuttling rate between trans-PR2 and cis-PR2 induced by molecular isomerization enables a light-gated ion transport, i.e., ON/OFF in situ regulation of transport activity and single-channel current. This work represents an example of using a photoswitchable molecular machine to realize gated ion transport, which demonstrates the value of molecular machines functioning in biomembranes.

Synthesis, self-assembly, metal binding properties of triazole azobenzene based polycatenar dyes through click chemistry

Two series of novel polycatenar dyes consisting of a triazole azobenzene core were synthesized efficiently by copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction. These compounds can self-assemble into SmC and Colhex/p6mm liquid-crystalline phases, and form multistimuli responsive organogels. Bicontinuous cubic phase (CubV) could be induced in the binary system of a bicatenar compound with SmC phase and a hexacatenar compound with Colhex/p6mm phase. Photophysical investigation indicates that these compounds have reversible photoresponsive properties in solution, liquid-crystalline and gel states. They can also act as chemosensors of Fe3+ and sodium dithionite with high selectivity.