201232-21-5Relevant academic research and scientific papers
The palladium catalyzed allylic alkylation of bis(trimethylsilyl) substituted propenyl acetates or carbonates in the presence of chiral ligands
Romero, Donna L.,Fritzen, Edward L.
, p. 8659 - 8662 (2007/10/03)
Palladium catalyzed asymmetric allylic alkylations of a bis(trimethylsilyl) substituted propenyl acetate and carbonate were investigated using various chiral ligands and reaction conditions. The best enantioselectivity (86% e.e.) was obtained with the substrate 1-phenyl-3,3-bis(trimethylsilyl)propenyl carbonate 13 and the chiral oxazoline ligand 4c.
