20125-66-0

Basic information

• Product Name: Silane, triethyl[(1-ethyl-1-methyl-3-phenyl-2-propynyl)oxy]-
• CAS NO: 20125-66-0
• Molecular Formula: C18H28OSi
• Molecular Weight: 288.505
• Mol File: 20125-66-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Silane, triethyl[(1-ethyl-1-methyl-3-phenyl-2-propynyl)oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, triethyl[(1-ethyl-1-methyl-3-phenyl-2-propynyl)oxy]-(20125-66-0)
• EPA Substance Registry System: Silane, triethyl[(1-ethyl-1-methyl-3-phenyl-2-propynyl)oxy]-(20125-66-0)

Safety Data

• Hazardous Substances Data: 20125-66-0(Hazardous Substances Data)

Upstream product

• 994-30-9 triethylsilyl chloride 
• 1966-65-0 3-methyl-1-phenyl-1-pentyn-3-ol 

Downstream Products

• 20125-68-2 3-methyl-1-phenyl-3-(triethylsilyl)oxypentane 
• 10415-87-9 3-methyl-1-phenylpentan-3-ol 

Relevant articles and documents

Solvent-modulated Pd/C-catalyzed deprotection of silyl ethers and chemoselective hydrogenation

Recently we have reported undesirable and frequent deprotection of the TBDMS protective group of a variety of hydroxyl functions occurred under neutral and mild hydrogenation conditions using 10% Pd/C in MeOH. The deprotection of silyl ethers is susceptible to significant solvent effect. TBDMS and TES protecting groups were selectively cleaved in the presence of acid-sensitive functional groups such as TIPS ether, TBDPS ether and dimethyl acetal under hydrogenation condition using 10% Pd/C in MeOH. In contrast, chemoselective hydrogenation of reducible functional groups such as acetylene, olefin and benzyl ether, proceeds in the presence of TBDMS or TES ethers in AcOEt or MeCN.