20127-07-5

Basic information

• Product Name: 6-oxaspiro[4.5]decan-7-one
• Synonyms: 6-oxaspiro[4.5]decan-7-one;Einecs 243-535-7
• CAS NO: 20127-07-5
• Molecular Formula: C₉H₁₄O₂
• Molecular Weight: 154.20626
• EINECS: 243-535-7
• Mol File: 20127-07-5.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 260.5°Cat760mmHg
• Flash Point: 102.7°C
• Appearance: /
• Density: 1.07g/cm³
• Vapor Pressure: 0.0122mmHg at 25°C
• Refractive Index: 1.488
• CAS DataBase Reference: 6-oxaspiro[4.5]decan-7-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-oxaspiro[4.5]decan-7-one(20127-07-5)
• EPA Substance Registry System: 6-oxaspiro[4.5]decan-7-one(20127-07-5)

Safety Data

• Hazardous Substances Data: 20127-07-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H14O2/c10-8-4-3-7-9(11-8)5-1-2-6-9/h1-7H2

Upstream product

• 108-55-4 glutaric anhydride, 
• 23708-47-6 1,4-bis(bromomagnesium)butane 
• 52318-90-8 1-(4-hydroxybutyl)cyclopentan-1-ol 
• 16133-77-0 1-(pent-4'-enyl)cyclopentan-1-ol 
• 147877-63-2 6-Oxa-spiro[4.5]decan-7-ol 
• 121108-82-5 4-[2-(3-Bromo-propyl)-oxiranyl]-butyric acid ethyl ester 
• 201230-82-2 carbon monoxide 
• 36399-21-0 1-allylcyclopentan-1-ol 
• 6244-40-2 trans-1-(1-propenyl)cyclopentanol 
• 124-38-9 carbon dioxide 
• 195154-30-4 1-(3-Phenylsulfanyl-propyl)-cyclopentanol 
• 108-94-1 cyclohexanone 
• 542-28-9 3,4,5,6-tetrahydro-2H-pyran-2-one 
• 120-92-3 cyclopentanone 

Relevant articles and documents

Reaction of Di(bromomagnesio)alkanes with Cyclic Dicarboxylic Acid Anhydrides

The reaction of the di(bromomagnesio)alkanes BrMg4MgBr and BrMg5MgBr with cyclic anhydrides produces spirolactones in one step in good yield.

A new synthesis of lactones from tertiary alkenylcarbinols by cobalt-catalyzed photocarbonylation under ambient conditions

In the presence of a Co catalyst, tertiary vinyl-, propenyl-, and allylcarbinols were chelatively cycloadded to carbon monoxide to produce lactones by xanthone-sensitized photoreaction in tetrahydrofuran, under CO at 1 atmosphere and at room temperature.At lower temperatures the isomerization of alkenyl-carbinols was suppressed and lactones were obtained with improved selectivity.The photoprocess was facilitated by addition of pyridine or hydrogen and retarded in presence of amines or phosphines.Mechanistic interpretations for the process and the accompanying effects are discussed.Key words: chelative carbonylation, photocarbonylation, carbonylation of olefins, lactones synthesis from alkenylalcohols.

The Key Role of Water in the Heterogeneous Permanganate Oxidation of ω-Hydroxy Alkenes

Potassium permanganate-copper sulphate in dichloromethane in the presence of a catalytic amount of water effects a smooth oxidative cyclization of ω-hydroxy alkenes to ω-lactones in good yields with the net loss of one or more carbon atoms in the procees.