201287-84-5Relevant academic research and scientific papers
New unnatural L-nucleoside enantiomers: From their stereospecific synthesis to their biological activities
Gosselin,Boudou,Griffon,Pavia,Pierra,Imbach,Aubertin,Schinazi,Faraj,Sommadossi
, p. 1389 - 1398 (2007/10/03)
Several purine and pyrimidine β-L-dideoxynucleosides were stereospecifically synthesized and their antiviral properties examined. Two of them, namely β-L-2',3'-dideoxyadenosine (β-L-ddA) and its 2',3'- didehydro derivative (β-L-d4A) were found to have significant anti-human immunodeficiency virus (HIV) and anti-hepatitis B virus (HSV) activities in cell culture.
