201341-17-5Relevant academic research and scientific papers
Inhibition of fucosyl transferase and fucosidase by a rigid bicyclic mimic of α-L-fucose
Beacham, Annabel R.,Smelt, Kathryn H.,Biggadike, Keith,Britten, Christopher J.,Hackett, Lucy,Winchester, Bryan G.,Nash, Robert J.,Griffiths, Rhodri C.,Fleet, George W.J.
, p. 151 - 154 (1998)
A rigid bicyclic analogue of α-L-fucose, prepared from a monoacetonide of L-gulonolactone in an overall yield of 36% without the need for column chromatography, is a potent inhibitor of fucosidases and a weak inhibitor of a fucosyl transferase.
