Tetrahedron Letters p. 151 - 154 (1998)
Update date:2022-08-03
Topics:
Beacham, Annabel R.
Smelt, Kathryn H.
Biggadike, Keith
Britten, Christopher J.
Hackett, Lucy
Winchester, Bryan G.
Nash, Robert J.
Griffiths, Rhodri C.
Fleet, George W.J.
A rigid bicyclic analogue of α-L-fucose, prepared from a monoacetonide of L-gulonolactone in an overall yield of 36% without the need for column chromatography, is a potent inhibitor of fucosidases and a weak inhibitor of a fucosyl transferase.
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