201343-18-2

Upstream product

• 120445-48-9 4-methylbenzaldehyde semicarbazone 
• 107-06-2 1,2-dichloro-ethane 
• 33621-60-2 2-amino-5-(4-methylphenyl)-1,3,4-oxadiazole 
• 75-15-0 carbon disulfide 

Relevant academic research and scientific papers

Spiro-heterocycles containing 1,3,4-oxadiazole: A convenient synthesis of 3-(5- Substitutedphenyl-l,3,4-oxadiazole-2-yl)-5,8-dithiaspiro[3,4]-octan-2-onesand 1,4-dithia-6-azaspiro[4,4]-nonan-7-ones

A new series of novel 3-(5-substituted phenyl-l,3,4-oxadiazole-2-yl)-5,8-dithiaspiro [3,4]-octan-2-ones and l,4-dithia-6- azaspiro[4,4]nonan-7-ones have been synthesized from a common intermediate, in good yields. These compounds have been screened for th

Synthesis of 5-aryl-2-[spiro-(1,3-dithiolane)-2,4'-(3'-chloro-2'-azetidinon)-1'-yl]-1,3,4-oxa(thia)diazoles and 5-aryl-2-[spiro-(1,3-dithiolane)-2,2'-(4'-thiazolidinon)-3'-yl]-1,3,4-oxa(thia)diazoles as antimicrobial agents

5-Aryl-2-[spiro-(1,3-dithiolane)-2,4'-(3'-chloro-2'-azetidinon)-1'-yl]-1,3,4-oxa(thia)diazoles 4 and 5-aryl-2-[spiro-(1,3-dithiolane)-2,2'-(4'-thiazolidinon)-3'-yl]-1,3,4-oxa(thia)diazoles 5 have been synthesised from 5-aryl-2-(1,3-dithiolan-2-yl)imino-1,3,4-oxa(thia)diazoles 3 with chloro acetyl chloride and mercapto acetic acid, respectively. These compounds have been screened on Aspergillus niger, Pyricularia oryzae, Fusarium oxysporum and Cephalosporum sacchari; and Escherichia coli, Salmonella typhi and Bacillus aureus for their antifungal and antibacterial activities, respectively.