201343-22-8Relevant academic research and scientific papers
Synthesis of 5-aryl-2-[spiro-(1,3-dithiolane)-2,4'-(3'-chloro-2'-azetidinon)-1'-yl]-1,3,4-oxa(thia)diazoles and 5-aryl-2-[spiro-(1,3-dithiolane)-2,2'-(4'-thiazolidinon)-3'-yl]-1,3,4-oxa(thia)diazoles as antimicrobial agents
Khan, Mukhtar Hussain,Nizamuddin
, p. 625 - 629 (2007/10/03)
5-Aryl-2-[spiro-(1,3-dithiolane)-2,4'-(3'-chloro-2'-azetidinon)-1'-yl]-1,3,4-oxa(thia)diazoles 4 and 5-aryl-2-[spiro-(1,3-dithiolane)-2,2'-(4'-thiazolidinon)-3'-yl]-1,3,4-oxa(thia)diazoles 5 have been synthesised from 5-aryl-2-(1,3-dithiolan-2-yl)imino-1,3,4-oxa(thia)diazoles 3 with chloro acetyl chloride and mercapto acetic acid, respectively. These compounds have been screened on Aspergillus niger, Pyricularia oryzae, Fusarium oxysporum and Cephalosporum sacchari; and Escherichia coli, Salmonella typhi and Bacillus aureus for their antifungal and antibacterial activities, respectively.
