201350-79-0Relevant academic research and scientific papers
Enantioselective α-alkylation of piperidine via chiral perhydropyrido [2,1-b] [1,3,4]-oxadiazinone: An easy route for the synthesis of both enantiomers of coniine
Pandey, Ganesh,Das, Parthasarathi
, p. 9073 - 9076 (2007/10/03)
Enantioselective direct alkylation of piperidine involving chiral perhydropyrido [2,1-b] [1,3,4]-oxadiazinone using either form of mandelic acid as chiral auxiliary is reported. The application of the strategy is demonstrated by the synthesis of(R)- as well as (S)- coniine.
