201354-06-5Relevant academic research and scientific papers
Charge and substituent effects on affinity and metabolism of benzbromarone-based CYP2C19 inhibitors
Locuson II, Charles W.,Suzuki, Hisashi,Rettie, Allan E.,Jones, Jeffrey P.
, p. 6768 - 6776 (2007/10/03)
Human cytochrome P450 (CYP) 2C19 is one of the most important CYP2C family members responsible for metabolizing commonly prescribed drugs. This research describes synthetic modifications to benzbromarone (Bzbr) to create the most potent CYP2C19 inhibitor
