20146-24-1

Usage

Uses

Used in Pharmaceutical Industry:
2-(2-FURYL)-6-METHYLQUINOLINE-4-CARBOXYLIC ACID is used as a pharmaceutical compound for its antimicrobial, antifungal, and anti-inflammatory properties, making it a candidate for the development of new drugs to treat various infections and inflammatory conditions.
Used in Organic Synthesis:
In the field of organic synthesis, 2-(2-FURYL)-6-METHYLQUINOLINE-4-CARBOXYLIC ACID is used as a building block for the synthesis of other complex organic compounds, contributing to the advancement of chemical research and the creation of novel molecules with potential applications.
Used in Biochemical and Biomedical Research:
2-(2-FURYL)-6-METHYLQUINOLINE-4-CARBOXYLIC ACID is used as a fluorescent probe in biochemical and biomedical research, enabling the study of various biological processes and interactions at the molecular level, which can lead to a better understanding of disease mechanisms and the development of targeted therapies.

Upstream product

• 98-01-1 furfural 
• 106-49-0 p-toluidine 
• 127-17-3 2-oxo-propionic acid 
• 1192-62-7 1-(2-furyl)-1-ethanone 
• 608-05-9 5-methyl-indole-2,3-dione 

Downstream Products

• 908562-54-9 C₂₁H₂₃N₃O₂ 

Relevant academic research and scientific papers

ACRIDINE AND QUINOLINE SIRTUIN MODULATORS

Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, chemo therapeutic induced neuropathy, neuropathy associated with an ischemic event, polyglutamine diseases, ocular diseases and/or disorders, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.

Synthesis, characterization and antibacterial activities of some N-bridged heterocycles containing triazole, quinoline and nitrofuran moieties

A series of 2-(2-furyl)4-quinolinecarboxylic acids (3), 2-(5-nitro-2-furyl)4-quinolinecarboxylic acids (6), 4-(3-aryloxymethyl-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazolo-6-yl)-2- (furyl)quinolines (5) and 4-(3-aryloxymethyl-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazolo-6-yl)-2- (5-nitro-2-furyl)quinolines (7) were synthesized. The structures of the newly synthesized compounds are confirmed on the basis of elemental analysis, IR, 1H-NMR and mass spectral data. The newly synthesized compounds are evaluated for their antibacterial activities. Compounds containing nitrofuran moiety showed excellent antibacterial activity. Results of such studies are disscussed in this paper.