201472-99-3Relevant academic research and scientific papers
3-Aryl-2-carbomethoxybicyclo[3.2.1]oct-2-enes inhibit WIN 35,428 binding potently and selectively at the dopamine transporter
Meltzer, Peter C.,Blundell, Paul,Huang, Hong,Liu, Shanghao,Yong, Yaw F.,Madras, Bertha K.
, p. 581 - 590 (2000)
The search for medications for cocaine abuse has focused upon the design of potential cocaine antagonists or cocaine substitutes which interact at the dopamine transporter of mammalian systems. This manuscript describes the synthesis and biological evalua
Synthesis and ligand binding of tropane ring analogues of paroxetine
Keverline-Frantz, Kathryn I.,Boja, John W.,Kuhar, Michael J.,Abraham, Philip,Burgess, Jason P.,Lewin, Anita H.,Carroll, F. Ivy
, p. 247 - 257 (2007/10/03)
(3S,4R)-4-(4-Fluoropheny)-3-[[3,4- (methylenedioxy)phenoxy]methyl]piperidine [(3S,9R)-3, paroxetine] is a selective serotonin reuptake inhibitor (SSRI) used as an antidepressant in humans. In previous studies, we reported that certain (1R)-3β-(substituted
