201553-45-9Relevant academic research and scientific papers
Synthesis of conformationally constrained potential inhibitors of mammalian metalloproteinases
Hanessian, Stephen,Griffin, Andrew,Devasthale, Pratik V.
, p. 3119 - 3124 (2007/10/03)
The synthesis of carbocyclic molecules containing functional groups capable of interacting with appropriate binding sites in certain metalloproteinases is described. Preliminary biological evaluation reveals modest inhibitory activity for a thioether analog in the trisubstituted cyclopropane series.
