201595-09-7

Upstream product

• 52978-83-3 2,3,4-trimethoxy-6-nitrobenzaldehyde 
• 2103-57-3 2,3,4-trimethoxybenzaldehyde 

Downstream Products

• 1334162-97-8 6-iodo-2,3,4-trimethoxybenzoic acid 
• 1752-02-9 methyl 6-iodo-2,3,4-trimethoxybenzoate 
• 1360789-67-8 methyl 2-hydroxy-6-iodo-3,4-dimethoxybenzoate 
• 82358-34-7 coeloginin 
• 481074-62-8 N-(6-formyl-3,4,5-trimethoxyphenyl)-chloroacetamide 

Relevant academic research and scientific papers

Polycationic ligands in gold catalysis: Synthesis and applications of extremely π-acidic catalysts

Very often ligands are anionic or neutral species. Cationic ones are rare, and, when used, the positively charged groups are normally appended to the periphery of the ligand. Here, we describe a dicationic phosphine with no spacer between the phosphorus atom and the two positively charged groups. This structural feature makes its donor ability poorer than that of phosphites and only comparable to extremely toxic or pyrophoric compounds such as PF 3 or P(CF3)3. By exploiting these properties, a new Au catalyst has been developed displaying a dramatically enhanced capacity to activate π-systems. This has been used to synthesize very sterically hindered and naturally occurring 4,5-disubstituted phenanthrenes. The present approach is expected to be applicable to the development and improvement of many other transition metal catalyzed transformations that benefit from extremely strong π-acceptor ligands. The mechanism of selected catalytic transformations has been explored by density functional calculations.

Cyclic diamine compound with condensed-ring groups

A cyclic diamine compound of formula (1): wherein R1 and R2 are individually a hydrogen atom or a methoxy group, provided R1 is a methoxy group when R2 is a hydrogen atom, or a hydrogen atom when R2 is a methoxy group; A is an oxygen atom, a sulfur atom, CH═CH, CH═N or NR3, in which R3 is a hydrogen atom, or a lower alkyl, hydroxy lower alkyl, lower alkoxy lower alkyl, aryl or aryl lower alkyl group; B is a nitrogen atom, CH or CR4, in which R4 is a hydrogen atom, or a lower alkyl, hydroxy lower alkyl, lower alkoxy lower alkyl, aryl or aryl lower alkyl group; m is 1 or 2; and n is a number of 1 to 5, an acid-addition salt thereof, or a hydrate thereof. The compound has inhibitory effects on cell adhesion and is useful for treatment of allergy, asthma, rheumatism, arteriosclerosis, and inflammation.