201608-41-5

Upstream product

• 96933-21-0 (RS)-2a,3,4,5-tetrahydro-1H-benz[cd]indol-2-one 
• 10338-69-9 1,2,3,6-tetrahydro-4-phenylpyridine 
• 201609-25-8 2a-(4-bromobutyl)-2a,3,4,5-tetrahydrobenz[cd]indole-2(1H)-one 
• 43064-12-6 1,2,3,6-tetrahydro-4-phenylpyridine hydrochloride 

Downstream Products

• 201608-40-4 C₂₆H₃₀N₂O*ClH 

Relevant academic research and scientific papers

New tetrahydrobenzindoles as potent and selective 5-HT7 antagonists with increased In vitro metabolic stability

Chemical modifications of compound 1 (DR4004), a potent, selective antagonist of the 5-HT7 receptor, were conducted with the aim of improving its metabolic stability. Halogenation of putative sites of oxidative metabolism afforded compounds 7-1

Tetrahydrobenzindole compounds

A compound of formula (I) for use in the treatment or prevention of mental diseases A is N, CH, C having a double bond or CR5; each of B and Z is independently N, CH or CR1, with the proviso that A is N when B and/or Z is N; R1, R2, R3, R4and R5and n are as defined in the specification.