201667-84-7

Upstream product

• 158817-33-5 (4S,5S,6R,1'R,1''S,2''S,3''S)-2,2-dimethyl-5-p-methoxybenzyloxy-4-(3'-p-methoxybenzyloxy-1'-methylpropyl)-6-(1'',2''-dimethyl-3'',4''-epoxybutyl)-1,3-dioxane 
• 70277-75-7 lithium acetylide 
• 320740-01-0 (R)-4-(4-methoxybenzyloxy)-2-methylbutanal 
• 158817-28-8 (2S,3S,4R,7R)-2-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-9-(4-methoxy-benzyloxy)-3,7-dimethyl-non-5-yn-4-ol 
• 158817-30-2 (4R,7S)-7-[(1S,2S)-2-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-1-methyl-propyl]-4-methyl-4,7-dihydro-3H-oxepin-2-one 
• 201667-72-3 methyl (2E)-5-(4-methoxybenzyloxy)-2-pentenoate 
• 201667-83-6 (4S,5S,6R,1'R,1''S,2''S,3''S)-2,2-dimethyl-5-p-methoxybenzyloxy-4-(3'-p-methoxybenzyloxy-1'-methylpropyl)-6-[1'',2''-dimethyl-3''-hydroxy-4''-(2,4,6-triisopropylbenzenesulfonyloxy)butyl]-1,3-dioxane 
• 201667-81-4 (4R,5S,6S)-4-[(1S,2S)-2-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-1-methyl-propyl]-5-(4-methoxy-benzyloxy)-6-[(R)-3-(4-methoxy-benzyloxy)-1-methyl-propyl]-2,2-dimethyl-[1,3]dioxane 
• 201667-82-5 (4S,5S,6R,1'R,1''S,2''S,3''S)-2,2-dimethyl-5-p-methoxybenzyloxy-4-(3'-p-methoxybenzyloxy-1'-methylpropyl)-6-(1'',2''-dimethyl-3'',4''-dihydroxybutyl)-1,3-dioxane 
• 158817-22-2 Benzoic acid (Z)-(1S,4R)-1-[(1S,2S)-2-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-1-methyl-propyl]-6-(4-methoxy-benzyloxy)-4-methyl-hex-2-enyl ester 
• 158817-31-3 (4R,4aS,8R,8aS)-4-[(1S,2S)-2-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-1-methyl-propyl]-2,2,8-trimethyl-tetrahydro-pyrano[3,2-d][1,3]dioxin-6-one 
• 158817-29-9 (Z)-(3R,6S,7S,8S)-8-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-6-hydroxy-3,7-dimethyl-non-4-enoic acid 
• 201667-80-3 (4R,5S,6S)-4-[(1S,2S)-2-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-1-methyl-propyl]-6-((R)-3-hydroxy-1-methyl-propyl)-2,2-dimethyl-[1,3]dioxan-5-ol 

Downstream Products

• 201667-93-8 (5S,6S)-6-{(4R,5S,6S)-5-(4-Methoxy-benzyloxy)-6-[(R)-3-(4-methoxy-benzyloxy)-1-methyl-propyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-5-methyl-hept-1-en-4-one 
• 158817-34-6 (4S,5S,6R,1'R,1''S,2''S,3''S)-2,2-dimethyl-5-p-methoxybenzyloxy-4-(3'-p-methoxybenzyloxy-1'-methylpropyl)-6-(1'',2''-dimethyl-3''-hydroxy-5''-hexenyl)-1,3-dioxane 

Relevant academic research and scientific papers

Synthetic studies on ciguatoxin [1]; construction of the spiro acetal part (C46-C55)

The spiro acetal part (C46-C55) of ciguatoxin was synthesized stereoselectively.

Construction of the C46-C55 Fragment of Ciguatoxin

The compound with all the necessary functional groups of the KLM ring system in ciguatoxin, which is one of the most complicated toxic substances of marine origin, was synthesized stereoselectively.The crucial steps involve construction of the ethynyl alc