201670-51-1

Basic information

• Product Name: (Z)-1-(tert-butyldiphenylsilyloxy)-6,7-epoxy-3,7-dimethylocta-2-ene
• Synonyms: (Z)-1-(tert-butyldiphenylsilyloxy)-6,7-epoxy-3,7-dimethylocta-2-ene
• CAS NO: 201670-51-1
• Molecular Weight: 408.656
• Mol File: 201670-51-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (Z)-1-(tert-butyldiphenylsilyloxy)-6,7-epoxy-3,7-dimethylocta-2-ene(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-1-(tert-butyldiphenylsilyloxy)-6,7-epoxy-3,7-dimethylocta-2-ene(201670-51-1)
• EPA Substance Registry System: (Z)-1-(tert-butyldiphenylsilyloxy)-6,7-epoxy-3,7-dimethylocta-2-ene(201670-51-1)

Safety Data

• Hazardous Substances Data: 201670-51-1(Hazardous Substances Data)

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 106-25-2 Nerol 
• 201670-50-0 (Z)-3-Bromo-8-(tert-butyl-diphenyl-silanyloxy)-2,6-dimethyl-oct-6-en-2-ol 
• 139109-03-8 (Z)-1-[(tert-butyldiphenylsilyl)oxy]-3,7-dimethyl-2,6-octadiene 

Downstream Products

• 68982-81-0 (2Z,6Z,10Z)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl phosphate 
• 5905-42-0 betulaprenol-8 
• 1056289-79-2 (2Z,6Z,10Z,14Z)-9-(benzenesulfonyl)-1-(tert-butyldiphenylsilyloxy)-16-chloro-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraene 
• 1056288-48-2 (2Z,6Z)-1-(tert-butyldiphenylsilyloxy)-8-chloro-3,7-dimethylocta-2,6-diene 
• 145208-09-9 (2Z,6E)-1-((tert-butyldiphenylsilyl)oxy)-3,7-dimethyl-2,6-nonadien-9-yl 4-methylbenzenesulfonate 
• 145208-10-2 (Z,Z)-1-((tert-butyldiphenylsilyl)oxy)-3,7-dimethyl-2,6-nonadien-9-yl 4-methylbenzenesulfonate 
• 145208-23-7 (2Z,6E)-<6-2H>-1-((tert-butyldiphenylsilyl)oxy)-3,7-dimethyl-2,6-nonadien-9-ol 
• 145208-24-8 (Z,Z)-<6-2H>-1-((tert-butyldiphenylsilyl)oxy)-3,7-dimethyl-2,6-nonadien-9-ol 
• 145208-25-9 (2Z,6E)-<6-2H>-3,7-dimethyl-2,6-nonadienyl-9-(((4-methylphenyl)sulfonyl)oxy)-1-ol 
• 145208-26-0 (Z,Z)-<6-2H>-3,7-dimethyl-2,6-nonadienyl-9-(((4-methylphenyl)sulfonyl)oxy)-1-ol 

Relevant articles and documents

N-GLYCOSYLATION OF PEPTIDES AND PROTEINS

A process for the production of a glycoconjugate by N-glycosylation of a protein or peptide comprising the sequence D/E-X-N-X-S/T, wherein each X is the same or different and is any natural amino acid other than proline, wherein the process comprises reacting the protein or peptide with a polyisoprenyl pyrophosphate of formula (I), or a salt thereof, in the presence of PglB: (I) to produce the glycoconjugate comprising the protein or peptide having a saccharide [SI] linked to the asparagine in the sequence D/E-X-N-X-S/T. Polyisoprenylpyrophosphates used as substrates in the biocatalytic process are also provided, as well as certain glycoconjugates.

Synthesis of moenocinol and its analogs using BT-sulfone in Julia-Kocienski olefination

Moenocinol (C25H42O), the acyclic terpenoid unsaturated lipid part of moenomycin antibiotics, was prepared by an expedient method, which comprised organometallic reaction, Julia-Kocienski olefination, and enolate carbon bond formation as the key steps. The starting materials, nerol and 3-butyn-1-ol, were elaborated to the benzothiazole sulfone 2 and aldehyde 3, and the subsequent Julia-Kocienski olefination occurred in a stereospecific manner to give the desired 6E-configuration of moenocinol. Moenocinol (1) was thus synthesized by 10 linear steps in 12% overall yield, and its analogs 23, 24, and 28 with different chain lengths and unsaturation degrees were also realized by the similar reaction sequences.

Farnesyl-diphosphate synthase. Catalysis of an intramolecular prenyl transfer with bisubstrate analogs

Bisubstrate analogs for isopentenyl diphosphate and dimethylallyl diphosphate were examined as substrates for farnesyl-diphosphate synthase. The hydrocarbon moieties of the normal substrates were joined by a one-carbon bridge that permits reaction between