20172-32-1

Basic information

• Product Name: Pentanamide, N-(4-methylphenyl)-
• CAS NO: 20172-32-1
• Molecular Formula: C12H17NO
• Molecular Weight: 191.273
• Mol File: 20172-32-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Pentanamide, N-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pentanamide, N-(4-methylphenyl)-(20172-32-1)
• EPA Substance Registry System: Pentanamide, N-(4-methylphenyl)-(20172-32-1)

Safety Data

• Hazardous Substances Data: 20172-32-1(Hazardous Substances Data)

Upstream product

• 106-49-0 p-toluidine 
• 2082-59-9 pentanoic anhydride 
• 110-59-8 pentanonitrile 
• 123726-16-9 bis(4-methylphenyl)iodonium trifluoromethanesulfonate 
• 1627148-42-8 1-(4-methylphenyl)pentan-1-imine 
• 73901-66-3 N,N-di-p-tolyl-thiourea 
• 109-52-4 valeric acid 
• 693-04-9 butyl magnesium bromide 
• 622-58-2 p-Tolylisocyanate 
• 638-29-9 n-valeryl chloride 

Relevant articles and documents

Hypervalent Iodine-Mediated Oxidative Rearrangement of N-H Ketimines: An Umpolung Approach to Amides

An umpolung approach to amides via hypervalent iodine-mediated oxidative rearrangement of N-H ketimines under mild reaction conditions is described. This strategy provides target amides with excellent selectivity in good yields. In addition, preliminary m

Preparation method of N-aryl amide compound

The invention discloses a preparation method of an N-aryl amide compound, which comprises the following steps: (1) putting diaryliodonium salt and Cu(OAc)2 into a Schlenk tube provided with a magneticstirring rod; (2) sequentially adding DCE, H2O and nitrile by using an injector, sealing the Schlenk tube, and stirring for reaction at 80 DEG C; (3) cooling the obtained solution to room temperature, and performing extraction with EtOAc; and combining organic layers, performing washing with saline water, and performing drying with anhydrous Na2SO4; and (4) removing volatile matters in vacuum, and purifying residues through column chromatography to obtain the N-aryl amide compound. Through a large number of experiments, a substrate with a simple structure is screened, the reaction conditionsare mild, the yield is high, the pollution is small, and the application prospect is wide.

N-Acyl-N-(4-chlorophenyl)-4-nitrobenzenesulfonamides: Highly selective and efficient reagents for acylation of amines in water

A variety of N-acyl-N-(4-chlorophenyl)-4-nitrobenzenesulfonamides (1a-e) were synthesized in one pot from 4-chloroaniline under solvent-free conditions and have been developed as chemoselective N-acylation reagents. Selective protection of primary amines in the presence of secondary amines, acylation of aliphatic amines in the presence of aryl amines, and monofunctionalization of primary-secondary diamines as well as selective N-acylation of amino alcohols using these reagents are described. All of the acylation reactions were carried out in water as a green solvent. High stability and easy preparation of these acylating reagents are other advantages of this method.