201730-84-9

Basic information

• Product Name: 3-((S)-2-Azido-2-phenyl-ethylamino)-2-((S)-1-hydroxy-2,2-dimethyl-propyl)-3H-quinazolin-4-one
• Synonyms: 3-((S)-2-Azido-2-phenyl-ethylamino)-2-((S)-1-hydroxy-2,2-dimethyl-propyl)-3H-quinazolin-4-one
• CAS NO: 201730-84-9
• Molecular Weight: 392.461
• Mol File: 201730-84-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-((S)-2-Azido-2-phenyl-ethylamino)-2-((S)-1-hydroxy-2,2-dimethyl-propyl)-3H-quinazolin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-((S)-2-Azido-2-phenyl-ethylamino)-2-((S)-1-hydroxy-2,2-dimethyl-propyl)-3H-quinazolin-4-one(201730-84-9)
• EPA Substance Registry System: 3-((S)-2-Azido-2-phenyl-ethylamino)-2-((S)-1-hydroxy-2,2-dimethyl-propyl)-3H-quinazolin-4-one(201730-84-9)

Safety Data

• Hazardous Substances Data: 201730-84-9(Hazardous Substances Data)

Upstream product

• 182160-14-1 2-((S)-1-Hydroxy-2,2-dimethyl-propyl)-3-((S)-2-phenyl-aziridin-1-yl)-3H-quinazolin-4-one 
• 201730-83-8 3-((R)-2-Chloro-2-phenyl-ethylamino)-2-((S)-1-hydroxy-2,2-dimethyl-propyl)-3H-quinazolin-4-one 

Downstream Products

• 312532-37-9 {(S)-2-[2-((S)-1-Hydroxy-2,2-dimethyl-propyl)-4-oxo-4H-quinazolin-3-ylamino]-1-phenyl-ethyl}-carbamic acid tert-butyl ester 
• 137102-30-8 (S)-N₁-tert-butoxycarbonyl-1-phenyl-1,2-ethanediamine 

Relevant articles and documents

Ring-opening of chiral N-(3,4-dihydro-4-oxoquinazolin-3-yl)-substituted aziridines (Q*-substituted aziridines): Access to Q*-free chirons

The presence of the quinazolin-4(3H)-one ring (Q*) in N-(Q*)-aziridines facilitates ring-opening by nucleophiles: removal of the Q* group from enantiopure ring-opened products gives useful chirons.