Ring-opening of chiral N-(3,4-dihydro-4-oxoquinazolin-3-yl)-substituted aziridines (Q-substituted aziridines): Access to Q-free chirons

DOI: 10.1016/S0040-4039(97)10586-X

Source and publish data:

Tetrahedron Letters p. 497 - 500 (1998)

Update date:2022-08-05

Topics:

Authors:

Atkinson, Robert S.

Ayscough, Andrew P.

Gattrell, William T.

Raynham, Tony M.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(97)10586-X

The presence of the quinazolin-4(3H)-one ring (Q*) in N-(Q*)-aziridines facilitates ring-opening by nucleophiles: removal of the Q* group from enantiopure ring-opened products gives useful chirons.

Full text of DOI:10.1016/S0040-4039(97)10586-X

Products guided by the article

Product name:3-((S)-2-Azido-2-phenyl-ethylamino)-2-((S)-1-hydroxy-2,2-dimethyl-propyl)-3H-quinazolin-4-one

Cas No:201730-84-9

R&D Labs maybe for 201730-84-9

Cerametek Materials（ShenZhen）Co., Ltd.

Contact:+86-755-2324.2554

Address:A3-#9, YongChuan Street, Suite 501
Zhuzhou Farshine Chemical Industry Co., Ltd

Contact:0086-731-28482786

Address:No. 1,Shui Xian Road, He Tang Dictrict,Hunan-412000,China
Jiangsu King Road New Materials Co., Ltd.

website:http://www.jskingroad.com

Contact:0519-85720726 0519-85720721 13584535752

Address:No.1,Weihua Road,Xinbei District,Changzhou City,Jiangsu Province
Hubei Danao Pharmaceutical Co.,Ltd.

website:http://www.danaopharm.com

Contact:+86-719-5251167

Address:Fandan Road,Danjiangkou,Hubei
shanghai jinshan pharmaceutical Co.,Ltd

Contact:021-57363011，13681638167

Address:No. 7966 Tingfeng Road,Jinshan,Shanghai,China

Relevant to this article

Hydrogen Bonding Phase-Transfer Catalysis with Potassium Fluoride: Enantioselective Synthesis of β-Fluoroamines

Doi:10.1021/jacs.8b12568
(2019)
Synthesis of asymmetric iron-pybox complexes and their application to aziridine forming reactions

Doi:10.1016/j.tetlet.2004.10.047
(2004)
Rasta resin-triphenylphosphine oxides and their use as recyclable heterogeneous reagent precursors in halogenation reactions

Doi:10.3762/bjoc.10.143
(2014)
Doi:10.1021/ja01030a068
(1969)
Phenylselenotris(trimethylsilyl)silane and phenyltellurotris(trimethylsilyl)silane: Versatile reagents for the preparation of phenylseleno- and phenyltelluro-formates

Doi:10.1039/a704402j
(1997)
A facile and highly efficient route to a traceless pi-arene chromium linker. Applications to synthetic and combinatorial chemistry.

Doi:10.1021/ol0166000
(2001)

Article Doi

Ring-opening of chiral N-(3,4-dihydro-4-oxoquinazolin-3-yl)-substituted aziridines (Q*-substituted aziridines): Access to Q*-free chirons

DOI: 10.1016/S0040-4039(97)10586-X

Source and publish data: