20176-04-9 Usage
Uses
Used in Pharmaceutical Industry:
3,4-Dihydro-7-Methoxy-1-naphthol Acetate is used as a key intermediate for the enantioselective formation of 2-Acetoxy-1-tetralones. This application is particularly important in the pharmaceutical industry, where the production of chiral molecules with specific configurations is crucial for the development of effective drugs with minimal side effects.
Used in Organic Synthesis:
In the field of organic synthesis, 3,4-Dihydro-7-Methoxy-1-naphthol Acetate is utilized as a versatile building block for the synthesis of a wide range of organic compounds. Its unique structure allows for various chemical reactions, enabling the creation of complex molecules with potential applications in various industries, such as pharmaceuticals, agrochemicals, and materials science.
Used in Chiral Chemistry Research:
3,4-Dihydro-7-Methoxy-1-naphthol Acetate is also used as a research tool in the field of chiral chemistry. Its ability to participate in enantioselective reactions makes it an invaluable compound for studying the mechanisms and outcomes of asymmetric synthesis, ultimately contributing to the advancement of this scientific discipline.
Check Digit Verification of cas no
The CAS Registry Mumber 20176-04-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,1,7 and 6 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 20176-04:
(7*2)+(6*0)+(5*1)+(4*7)+(3*6)+(2*0)+(1*4)=69
69 % 10 = 9
So 20176-04-9 is a valid CAS Registry Number.
20176-04-9Relevant academic research and scientific papers
Palladium-Catalyzed Intermolecular Oxyarylation of Vinylacetates with Retention of an Alkenyl Moiety
Qiu, Sheng-Qi,Xu, Yun-He,Loh, Teck-Peng
supporting information, p. 3462 - 3465 (2015/07/28)
Palladium-catalyzed intermolecular oxyarylation reaction of vinylacetates with retention of the double bond in the final product is developed. Under the optimized reaction conditions, the desired products of multisubstituted vinylesters could be obtained
Inhibitors of acyl CoA:cholesterol acyltransferase
Vaccaro, Wayne,Amore, Cindy,Berger, Joel,Burrier, Robert,Clader, John,Davis, Harry,Domalski, Martin,Fevig, Tom,Salisbury, Brian,Sher, Rosy
, p. 1704 - 1719 (2007/10/03)
Conformational restriction of previously disclosed acyclic diphenylethyl)diphenylacetamides led to the discovery of several potent inhibitors of acyl CoA:cholesterol acyltransferase (ACAT). cis-[2-(4- Hydroxyphenyl)-1-indanyl]diphenylacetamide (4a) was the most potent ACAT inhibitor identified (IC50 = 0.04 μM in an in vitro rat hepatic microsomal ACAT assay, ED50 = 0.72 mg/kg/day in cholesterol-fed hamsters).