20177-64-4Relevant academic research and scientific papers
The crystal structures of some 1-aryl-5-methyl-1,2,3-triazole derivatives
Dong, Heng-Shan,Dong, Hong-Ru,Zhang, Tong-Qiang
, p. 32 - 35 (2009)
The two 1-aryl-5-methyl-1,2,3-triazole derivatives were prepared by the 1-aryl-5-methyl-1,2,3-triazol-4-carboxylic acids 3. The yielded products 4a-b were confirmed by NMR, MS, IR spectra. We investigated the crystalline structure of compounds 4a and 4b.
KINASE MODULATORS AND METHODS OF USE THEREOF
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Page/Page column 163; 181-182, (2022/01/20)
The present invention relates to novel compounds that modulate the activity of one or more kinases, such as TYK2 or mutants thereof. The compounds, which may be kinase inhibitors or activators, are useful for treating autoimmune diseases, such as, such as psoriasis, lupus, multiple sclerosis, and inflammatory bowel disease.
PYRROLO[2,3-B]PYRIDINES AS HPK1 INHIBITOR AND USES THEREOF
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Page/Page column 87, (2020/06/10)
Disclosed herein is a compound of Formula (I), or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, and pharmaceutical compositions comprising thereof. Also disclosed is a method of treating HPK1 related disorders or diseases by using the compound disclosed herein.
Regioselective N/C-heterocyclization of allenylindium bromide across aryl azides: One-pot synthesis of 5-methyl-1,2,3-triazoles
Banday, Abid H.,Hruby, Victor J.
, p. 1859 - 1862 (2014/08/18)
An unprecedented, one-pot regioselective synthesis of 1,5-disubstituted 1,2,3-triazoles through N/C-heterocyclization of allenylindium bromide across aryl azides is described. The synthesis is carried out under mild conditions in aqueous medium and procee
