20725-34-2Relevant articles and documents
Synthesis and antibacterial activity of di-heteryl substitued [1,2,4]triazolo [3,4-b] [1,3,4]thiadiazoles
Sanjeeva Reddy,Vani Devi,Sunitha,Kalyani,Nagaraj
, p. 590 - 597 (2017/01/18)
A new series of 3-(5-methyl-1-phenyl-1H-4-pyrazolyl)-6-(5-methyl-1-aryl-1H-1,2,3-triazol-4-yl)[1,2,4]triazolo [3,4-b][1,3,4]thiadiazoles 12a-j have been prepared and assayed for their antibacterial activity against human pathogenic Gram-positive bacteria viz., Staphylococcus aureus, Bacillus subtilis and Gram-negative Escherichia coli. Among the screened compounds 12b, 12c and 12f, in which phenyl ring of triazole moiety bear 4-chloro, 4-nitro and 4-fluoro substituents respectively, showed high activity against all the micro-organisms employed. The activities of these compounds are almost equal to the standards.
N-ARYLTRIAZOLE COMPOUNDS AS LPAR ANTAGONISTS
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, (2014/01/09)
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of inflammatory diseases and disorders such as, for example, pulmonary fibrosis
The crystal structures of some 1-aryl-5-methyl-1,2,3-triazole derivatives
Dong, Heng-Shan,Dong, Hong-Ru,Zhang, Tong-Qiang
experimental part, p. 32 - 35 (2009/06/06)
The two 1-aryl-5-methyl-1,2,3-triazole derivatives were prepared by the 1-aryl-5-methyl-1,2,3-triazol-4-carboxylic acids 3. The yielded products 4a-b were confirmed by NMR, MS, IR spectra. We investigated the crystalline structure of compounds 4a and 4b.