201792-91-8

Basic information

• Product Name: Propanoic acid, 3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2-methyl-, (2R)-
• CAS NO: 201792-91-8
• Molecular Formula: C20H26O3Si
• Molecular Weight: 342.51
• Mol File: 201792-91-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2-methyl-, (2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2-methyl-, (2R)-(201792-91-8)
• EPA Substance Registry System: Propanoic acid, 3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-2-methyl-, (2R)-(201792-91-8)

Safety Data

• Hazardous Substances Data: 201792-91-8(Hazardous Substances Data)

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 95514-04-8 (S)-3-(tert-butyldiphenylsilyloxy)-2-methylpropan-1-ol 
• 95514-03-7 (R)-methyl 3-(tert-butyl(diphenyl)silyloxy)-2-methylpropanoate 

Downstream Products

• 1362028-64-5 C₂₃H₃₀O₅Si 
• 720707-68-6 (R)-3-(tert-Butyl-diphenyl-silanyloxy)-2-methyl-propionic acid (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenyl ester 

Relevant articles and documents

The amido-pentadienoate-functionality of the rakicidins is a thiol reactive electrophile - Development of a general synthetic strategy

We demonstrate that a unique class-defining functionality (mc-APD) found in macrocyclic natural products with potent anti-cancer activity, imparts these compounds with electrophilic reactivity. The mc-APD group represents an interesting structural hybrid between canonical biologically relevant Michael-acceptors. Further, a novel thiol-elimination method for preparation of the mc-APD group is outlined.

Synthesis and CB1 receptor activities of novel arachidonyl alcohol derivatives

Novel derivatives of arachidonyl alcohol were synthesized and evaluated for their CB1 receptor activity by [35S]GTPγS assay using rat cerebellar membranes.