201856-57-7 Usage
Uses
(3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-Dimethylethyl ester is used as a reagent in the synthesis of abeo-taxane derivatives that possess broad inhibitory effects against proliferation of colon cancer, melanoma, and renal cancer cell lines. (3R,4S)-3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-Dimethylethyl ester is also used as a reagent in the synthesis of a novel D-ring modified Docetaxel (D494420) analogue which has proven to have equipotent cytotoxicity in relation to Paclitaxel (P132500) towards cancer cell lines.
Check Digit Verification of cas no
The CAS Registry Mumber 201856-57-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,1,8,5 and 6 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 201856-57:
(8*2)+(7*0)+(6*1)+(5*8)+(4*5)+(3*6)+(2*5)+(1*7)=117
117 % 10 = 7
So 201856-57-7 is a valid CAS Registry Number.
InChI:InChI=1/C18H25NO5/c1-6-22-12(2)23-15-14(13-10-8-7-9-11-13)19(16(15)20)17(21)24-18(3,4)5/h7-12,14-15H,6H2,1-5H3
201856-57-7Relevant articles and documents
A [...] he [...] synthesis process
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Paragraph 0013, (2019/04/06)
A [...] he [...] synthesis process, in order to (3 R, 4 S) - 3 - hydroxy - 4 - phenyl - 2 - azetidinone as the starting material, adopts the one-pot synthesis, its first with vinyl ether condensation, with the BOC - anhydride is condensed directly [...] h
Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
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, (2008/06/13)
The present invention is directed to novel taxanes useful as chemotherapeutic agents or their precursors. Processes for preparing the novel taxanes include coupling reactions, in the presence of a base, of baccatin of formula (III) or (IV) STR1 with β-lac