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Methyl 3-(hydroxymethyl)-4-nitrobenzoate is a versatile benzoic acid derivative featuring a methyl, hydroxymethyl, and nitro group attached to a benzene ring. Its unique structure and potential biological activity make it a valuable compound in organic synthesis and pharmaceutical research.

201932-92-5

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201932-92-5 Usage

Uses

Used in Organic Synthesis:
Methyl 3-(hydroxymethyl)-4-nitrobenzoate serves as a key building block in the synthesis of various chemical products. Its hydroxymethyl and nitro groups contribute to its versatility, allowing for the creation of a wide range of compounds.
Used in Pharmaceutical Research:
Due to its potential biological activity, methyl 3-(hydroxymethyl)-4-nitrobenzoate is utilized in pharmaceutical research for the development of new drugs. Its unique structure and functional groups make it a promising candidate for further exploration and application in the pharmaceutical industry.
Used in the Synthesis of Pharmaceuticals:
Methyl 3-(hydroxymethyl)-4-nitrobenzoate is employed as a crucial intermediate in the synthesis of various pharmaceuticals. Its presence in the molecular structure of these compounds contributes to their therapeutic properties and effectiveness.
Used in the Synthesis of Agrochemicals:
In addition to its applications in pharmaceuticals, methyl 3-(hydroxymethyl)-4-nitrobenzoate is also used as a building block in the synthesis of agrochemicals. Its versatile structure allows for the development of compounds with potential applications in agriculture and pest control.

Check Digit Verification of cas no

The CAS Registry Mumber 201932-92-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,1,9,3 and 2 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 201932-92:
(8*2)+(7*0)+(6*1)+(5*9)+(4*3)+(3*2)+(2*9)+(1*2)=105
105 % 10 = 5
So 201932-92-5 is a valid CAS Registry Number.

201932-92-5Relevant articles and documents

PRODRUG-TYPE ANTICANCER AGENT USING CANCER-SPECIFIC ENZYMATIC ACTIVITY

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Paragraph 0224, (2021/01/22)

To provide novel compounds that are promising as prodrug-type anticancer agents, a compound represented by general formula (I) or a salt thereof is provided.

Discovery and Structure-Activity Relationships of the Neoseptins: A New Class of Toll-like Receptor-4 (TLR4) Agonists

Morin, Matthew D.,Wang, Ying,Jones, Brian T.,Su, Lijing,Surakattula, Murali M. R. P.,Berger, Michael,Huang, Hua,Beutler, Elliot K.,Zhang, Hong,Beutler, Bruce,Boger, Dale L.

supporting information, p. 4812 - 4830 (2016/06/13)

Herein, we report studies leading to the discovery of the neoseptins and a comprehensive examination of the structure-activity relationships (SARs) of this new class of small-molecule mouse Toll-like receptor 4 (mTLR4) agonists. The compounds in this class, which emerged from screening an α-helix mimetic library, stimulate the immune response, act by a well-defined mechanism (mouse TLR4 agonist), are easy to produce and structurally manipulate, exhibit exquisite SARs, are nontoxic, and elicit improved and qualitatively different responses compared to lipopolysaccharide, even though they share the same receptor.

NEOSEPTINS: SMALL MOLECULE ADJUVANTS

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Page/Page column 138, (2014/09/03)

A MD-2:TLR4 complex agonist compound is disclosed whose structure corresponds to Formula (I), as defined within. Also disclosed are a method of its preparation and use, as well as a pharmaceutical composition containing the same.

FLUORINATED ARYLAMIDE DERIVATIVES

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Page/Page column 67, (2008/06/13)

The present invention relates to a novel class of fluorinated arylamide derivatives. The instant compounds can be used to treat cancer. The fluorinated arylamide derivatives can also inhibit histone deacetylase and are suitable for use in selectively indu

Use of certain amides as probes for detection of antitubulin activity and resistance monitoring

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, (2008/06/13)

This invention relates to methods for screening compounds for antitubulin activity, evaluation of cells for sensitivity to antitubulin drugs, resistance monitoring and quantifying tubulin using certain amides that inhibit the growth of eukaryotic cells as

Process for the manufacture of acetonylbenzamides

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, (2008/06/13)

Novel routes for the preparation of acetonylbenzamides are provided by the reaction of an amine and acyl chloride. Novel routes to various intermediates used in the manufacture of acetonylbenzamides are also disclosed.

Fungicidically active N-acetonylbenzamide compounds

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, (2008/06/13)

Novel N-acetonylbenzamides are disclosed. These compounds are useful in controlling phytopathogenic fungi.

Methods for controlling algae

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, (2008/06/13)

A method for controlling algae and marine fouling organisms is described. The method employs N-acetonylbenzamides compounds provided in an effective amount to kill or inhibit the growth of the algae or fouling organisms.

Process for the manufacture of acetonylbenzamides

-

, (2008/06/13)

Novel routes for the preparation of acetonylbenzamides are provided by the reaction of an amine and acyl chloride. Novel routes to various intermediates used in the manufacture of acetonylbenzamides are also disclosed.

Method for inhibiting the growth of mammalian cells

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, (2008/06/13)

A method for inhibiting mammalian cell growth is disclosed. The method uses compounds known as N-acetonylarylamides. The compounds have been shown to inhibit cell mitosis and to inhibit microtubule assembly. The method may be used to treat diseases associated with rapid cell growth, particularly cancer. The compounds used in the method of the present invention may be used in combination with other therapies and may be administered by known techniques for drug administration.

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