202065-44-9Relevant academic research and scientific papers
Investigations on New Strategies for the Facile Synthesis of Polyfunctionalized Phosphinates: Phosphinopeptide Analogues of Glutathionylspermidine
Chen, Shoujun,Coward, James K.
, p. 502 - 509 (2007/10/03)
Three possible methods for the facile synthesis of functionalized phosphinates, including the core of complex phosphinopeptide analogues of glutathionylspermidine, were explored. Among these methods, the three-component condensation reaction involving ben
Novel inhibitors of trypanothione biosynthesis: Synthesis and evaluation of a phosphinate analog of glutathionyl spermidine (GSP), a potent, slow-binding inhibitor of GSP synthetase
Chen, Shoujun,Lin, Chun-Hung,Walsh, Christopher T.,Coward, James K.
, p. 505 - 510 (2007/10/03)
A phosphinate analog of glutathionyl spermidine (Gsp), 3, has been synthesized and evaluated as an inhibitor of Gsp synthetase (GSPS). In addition, a non-spermidine-containing derivative (4) was synthesized in order to evaluate the role of the polyamine m
