2021-97-8

Basic information

• Product Name: 6-deoxy-6-fluoro-1,2:3,4-di-O-isopropylidene-α-D-galctopyranose
• CAS NO: 2021-97-8
• Molecular Weight: 262.278
• Mol File: 2021-97-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-deoxy-6-fluoro-1,2:3,4-di-O-isopropylidene-α-D-galctopyranose(CAS DataBase Reference)
• NIST Chemistry Reference: 6-deoxy-6-fluoro-1,2:3,4-di-O-isopropylidene-α-D-galctopyranose(2021-97-8)
• EPA Substance Registry System: 6-deoxy-6-fluoro-1,2:3,4-di-O-isopropylidene-α-D-galctopyranose(2021-97-8)

Safety Data

• Hazardous Substances Data: 2021-97-8(Hazardous Substances Data)

Upstream product

• 4064-06-6 1,2:3,4-di-O-isopropylidene-α-D-galactopyranose 
• 500131-50-0 N,N-diethyl-α,α-difluoro-(meta-methylbenzyl)amine 

Downstream Products

• 4536-07-6 6-Deoxy-6-fluor-galactose 
• 447-25-6 6-deoxy-6-fluoro-D-galactopyranose 
• 155488-15-6 1,2,3,4-tetra-O-acetyl-6-deoxy-6-fluoro-D-galactopyranose 
• 118396-37-5 1,2,3,4-tetra-O-acetyl-6-deoxy-6-fluoro-β-D-galactopyranose 
• 1191118-29-2 N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2-deoxy-4,6-O-benzylidene-3-O-[2,3,4-tri-O-acetyl-6-deoxy-6-fluoro-β-D-galactopyranosyl])-α-D-galactopyranosyl-L-threonine-tert-butyl ester 

Relevant articles and documents

Selective synthesis of fluorinated carbohydrates using N,N-diethyl-α, α-difluoro-(m-methylbenzyl)amine

Deoxyfluorination of a hydroxy group in carbohydrates was carried out using N,N-diethyl-α,α-difluoro-(m-methylbenzyl)amine. A primary hydroxy group in carbohydrates was effectively converted to the corresponding fluoride under microwave irradiation or at 100°C. Deoxyfluorination of hydroxy groups at the anomeric position proceeded at below room temperature, and glycosyl fluorides could be obtained in good yields. The reaction chemoselectively proceeded, and various protecting groups of carbohydrates can survive under the reaction conditions.