202124-58-1

Basic information

• Product Name: 1-(4-benzylpiperidinecarbonyl)methyl-5-cyanobenzimidazole
• Synonyms: 1-(4-benzylpiperidinecarbonyl)methyl-5-cyanobenzimidazole
• CAS NO: 202124-58-1
• Molecular Weight: 358.443
• Mol File: 202124-58-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(4-benzylpiperidinecarbonyl)methyl-5-cyanobenzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-benzylpiperidinecarbonyl)methyl-5-cyanobenzimidazole(202124-58-1)
• EPA Substance Registry System: 1-(4-benzylpiperidinecarbonyl)methyl-5-cyanobenzimidazole(202124-58-1)

Safety Data

• Hazardous Substances Data: 202124-58-1(Hazardous Substances Data)

Upstream product

• 6287-83-8 5-cyano-benzimidazole 
• 260253-93-8 (4-benzylpiperidinecarbonyl)methylene chloride 
• 64-18-6 formic acid 
• 221289-91-4 3-amino-4-[2-(4-benzyl-piperidin-1-yl)-2-oxo-ethylamino]-benzonitrile 
• 6393-40-4 4-Amino 3-nitro-benzonitrile 
• 939-80-0 4-chloro-3-nitrobenzonitrile 

Relevant articles and documents

Design and synthesis of potent and selective 5,6-fused heterocyclic thrombin inhibitors

Thrombin, a serine protease, plays a central role in the initiation of thrombotic events. We report design, synthesis, and antithrombotic efficacy of XU817 (7), a nonpeptide 5-(amidino) indole thrombin inhibitor. Utilizing the co-crystal structure of XU817 bound in the active site of thrombin we were able to synthesize analogs with enhanced thrombin affinity.