202127-65-9Relevant academic research and scientific papers
Oligonucleotide analogues with 4-hydroxy-N-acetylprolinol as sugar substitute
Ceulemans, Griet,Van Aerschot, Arthur,Wroblowski, Berthold,Rozenski, Jef,Hendrix, Chris,Herdewijn, Piet
, p. 1997 - 2010 (1997)
Modified oligonucleotides incorporating trans-4-hydroxy-N-acetyl-L-prolinol (trans-4-HO-L-NAP) or its D-analogue as sugar substitute were synthesised with adenine and thymine as nucleobases. All-adenine oligonucleotides built from (2S,4S) or (2R,4R)-cis-4
