Oligonucleotide analogues with 4-hydroxy-N-acetylprolinol as sugar substitute

DOI: 10.1002/chem.19970031215

Source and publish data:

Chemistry - A European Journal p. 1997 - 2010 (1997)

Update date:2022-08-04

Topics:

Authors:

Ceulemans, Griet

Van Aerschot, Arthur

Wroblowski, Berthold

Rozenski, Jef

Hendrix, Chris

Herdewijn, Piet

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/chem.19970031215

Modified oligonucleotides incorporating trans-4-hydroxy-N-acetyl-L-prolinol (trans-4-HO-L-NAP) or its D-analogue as sugar substitute were synthesised with adenine and thymine as nucleobases. All-adenine oligonucleotides built from (2S,4S) or (2R,4R)-cis-4

Full text of DOI:10.1002/chem.19970031215

Products guided by the article

Product name:1-(2-{(2R,4R)-4-Hydroxy-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-pyrrolidin-1-yl}-2-oxo-ethyl)-5-methyl-1H-pyrimidine-2,4-dione

Cas No:202127-65-9

R&D Labs maybe for 202127-65-9

HAORUI ENTERPRISES LLC

Contact:(1) 206-3550089

Address:5115 NE 8TH PL, Renton, WA 98059 USA
shandong zhongke taidou chemical co.,ltd

Contact:86-531-88682301

Address:Jinan shandong Province CHina
Shanghai Xinda Pharmaceuticals Co., Ltd.

Contact:86-21-33692333-8008

Address:999 Linxian Road, Jinshan Industrial Park, Shanghai, China
Daqing E-shine Chemical Co.,LTD

Contact:0086-024-31285112

Address:Hongweiyuan area, Ranghulu district
Shanghai Zhihua ChemTech Co., Ltd.

Contact:+86-13774313779

Address:Room 817 Suite B 3333 Shenjiang Road

Relevant to this article

Studies directed towards the total synthesis of the antibiotic macrodiolide tartrolon: EPC synthesis of the protected seco acid

Doi:10.1016/S0040-4039(97)10761-4
(1998)
Photocontrol of Antibacterial Activity: Shifting from UV to Red Light Activation

Doi:10.1021/jacs.7b09281
(2017)
Synthesis and structural studies of novel fused seven-membered carbocycles derived from exo-2-oxazolidinone dienes through (4+3) cycloadditions

Doi:10.1016/j.tet.2014.12.065
(2015)
Protonation Reactions of trans-M(H)(SPh)(dppe)₂ (M = Ru, Os) to Give Thiol and Dihydrogen Complexes. X-ray Crystal Structure Determination of trans-Ru(H)(SPh)(dppe)₂ and trans-[Os(H)(O₂)(dppe)₂](O₃SCF₃)

Doi:10.1021/ic971050g
(1998)
Total synthesis of antibiotic, micrococcin P, from 2,3,6-polythiazolesubstituted pyridine skeleton [fragment A-C]

Doi:10.1246/cl.1998.139
(1998)
Dipeptides with 3-(trimethylstannyl)alanine building blocks: Synthesis, characterization, and reactivity

Doi:10.1007/s00706-012-0902-6
(2013)

Article Doi