Oligonucleotide analogues with 4-hydroxy-N-acetylprolinol as sugar substitute

DOI: 10.1002/chem.19970031215

Source and publish data:

Chemistry - A European Journal p. 1997 - 2010 (1997)

Update date:2022-08-04

Topics:

Authors:

Ceulemans, Griet

Van Aerschot, Arthur

Wroblowski, Berthold

Rozenski, Jef

Hendrix, Chris

Herdewijn, Piet

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/chem.19970031215

Modified oligonucleotides incorporating trans-4-hydroxy-N-acetyl-L-prolinol (trans-4-HO-L-NAP) or its D-analogue as sugar substitute were synthesised with adenine and thymine as nucleobases. All-adenine oligonucleotides built from (2S,4S) or (2R,4R)-cis-4

Full text of DOI:10.1002/chem.19970031215

Products guided by the article

Product name:1-(2-{(2R,4R)-4-Hydroxy-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-pyrrolidin-1-yl}-2-oxo-ethyl)-5-methyl-1H-pyrimidine-2,4-dione

Cas No:202127-65-9

R&D Labs maybe for 202127-65-9

Hunan Dinuo Pharmaceutical Co.,Ltd.

Contact:86-731-88280100*8561

Address:Bio-pharmaceutical industrial park, Liuyang, Hunan, China
SPE Chemicals Co.,Ltd

Contact:

Address:ROOM 1715, No#345 Jin Xiang Road, Pudong District
Changzhou Litong Chemical Co., Ltd.

website:http://www.litonchem.com/

Contact:+86-519-86301238

Address:Laoba Rd, Hutang town Changzhou Jiangsu
Jiangsu Fengshan Group Co., Ltd.

Contact:86-25-86558671

Address:1903,Central International Mansion 105-6 North Zhongshan Road, Nanjing, China
Kunshan Yalong Trading Co,.Ltd

Contact:86-512-57621185

Address:805-807 Room Hongqiao Mansion ,1088 West Qianjin Road, Kunshan, Jiangsu，China

Relevant to this article

Studies directed towards the total synthesis of the antibiotic macrodiolide tartrolon: EPC synthesis of the protected seco acid

Doi:10.1016/S0040-4039(97)10761-4
(1998)
Photocontrol of Antibacterial Activity: Shifting from UV to Red Light Activation

Doi:10.1021/jacs.7b09281
(2017)
Synthesis and structural studies of novel fused seven-membered carbocycles derived from exo-2-oxazolidinone dienes through (4+3) cycloadditions

Doi:10.1016/j.tet.2014.12.065
(2015)
Protonation Reactions of trans-M(H)(SPh)(dppe)₂ (M = Ru, Os) to Give Thiol and Dihydrogen Complexes. X-ray Crystal Structure Determination of trans-Ru(H)(SPh)(dppe)₂ and trans-[Os(H)(O₂)(dppe)₂](O₃SCF₃)

Doi:10.1021/ic971050g
(1998)
Total synthesis of antibiotic, micrococcin P, from 2,3,6-polythiazolesubstituted pyridine skeleton [fragment A-C]

Doi:10.1246/cl.1998.139
(1998)
Dipeptides with 3-(trimethylstannyl)alanine building blocks: Synthesis, characterization, and reactivity

Doi:10.1007/s00706-012-0902-6
(2013)

Article Doi