202134-46-1Relevant academic research and scientific papers
The first asymmetric synthesis of (1R,1′S)-1-[1′-(benzyloxycarbonyl-methylamino)-2′-phenylethyl] oxirane: A promising building block for the synthesis of peptide mimics
Beier, Christian,Schaumann, Ernst,Adiwidjaja, Gunadi
, p. 41 - 42 (1998)
The threo N-methyl oxirane 5 was prepared from (S)-N-methyl phenylalanine by bromoketone reduction or by epoxidation routes. The unexpected stereochemical result of the reduction of bromoketone 7 leading to the threo isomer is discussed.
