2022-80-2

Usage

Uses

Used in Chemical Synthesis:
1,2,4-TRIBROMO-1,1,2-TRIFLUOROBUTANE is utilized as an intermediate in chemical synthesis processes, serving as a key component in the production of various chemical products.
Used as a Solvent:
1,2,4-TRIBROMO-1,1,2-TRIFLUOROBUTANE is employed as a solvent in certain industrial applications, where its unique properties allow for the dissolution of specific substances that may be difficult to dissolve in other solvents.
Used as a Refrigerant:
1,2,4-TRIBROMO-1,1,2-TRIFLUOROBUTANE is also used in refrigeration systems, where its properties contribute to the cooling process. However, due to its flammability and toxicity, it must be handled with extreme caution to prevent accidents and health hazards.
In the Chemical Industry:
1,2,4-TRIBROMO-1,1,2-TRIFLUOROBUTANE is used as a chemical intermediate for the synthesis of various compounds, contributing to the development of new materials and products.
In the Solvent Industry:
It is used as a solvent for specific applications, where its unique solvency properties are required for the dissolution of certain substances.
In the Refrigeration Industry:
1,2,4-TRIBROMO-1,1,2-TRIFLUOROBUTANE is used as a refrigerant in cooling systems, enhancing the efficiency of the refrigeration process.
Proper safety measures, including the use of personal protective equipment and adherence to safety protocols, are essential when working with 1,2,4-TRIBROMO-1,1,2-TRIFLUOROBUTANE to minimize the risks associated with its flammability and toxicity.

InChI:InChI=1/C4H4Br3F3/c5-2-1-3(6,8)4(7,9)10/h1-2H2

Upstream product

• 75-62-7 Bromotrichloromethane 
• 10493-44-4 1,1,2-trifluoro-4-bromobut-1-ene 
• 67-56-1 methanol 
• 235106-11-3 4-chloro-1,1,2-trifluorobut-1-ene 
• 1030386-64-1 1,2-dibromo-4-iodo-1,1,2-trifluorobutane 

Relevant academic research and scientific papers

Fluorinated butatrienes

Major improvements in the synthesis of 1,1,4,4-tetrafluorobutatriene (1) are presented. Despite many attempts to isolate new metal complexes of 1 only an iron complex containing a ligand which is composed of a partially hydrolyzed tetrafluorobutatriene-dimer and carbon monoxide could be isolated and characterized by X-ray crystallography. Certain metal centers and solvents accelerate the decomposition of 1. First attempts to synthesize 1,1-difluorobutatriene (2) are presented which underline the major challenges of a successful synthesis of 2.

Rearrangement of 3-membered 1,1,2-trifluorobromonium and iodonium ions and comparison of trifluorochloronium to fluorocarbenium ions

(Chemical Equation Presented) Reactions of chlorine (Cl2) with 4-halo-1,1,2-trifluorobut-1-enes (1, 2, or 3) give open-ion intermediates A and E that are in equilibrium. The open-chloronium ions (E) rearrange to a five-membered-ring halonium ion during ionic chlorination of 3 when the number-4 halo-substituent is iodine. Three-membered-ring bromonium and iodonium ions from alkenes 1, 2, or 3 are rather symmetrical and similar in structure. Quantum chemical calculations show that five-membered-ring halonium ion intermediates are 11 to 27 kcal/mol more stable than the three-membered-ring halonium ions or the open-ions A and E. The five-membered-ring intermediates lead to rearranged products. Rearranged products increase as the number-4 halogen (Z) becomes more nucleophilic (Z: Cl Br I). Open chloronium ions from ionic chlorination of terminal fluorovinyl alkenes are compared to the open ions generated by protons to similar alkenes.

Ionic reaction of halogens with terminal alkenes: The effect of electron-withdrawing fluorine substituents on the bonding of halonium ions

Ionic reactions of terminal alkenes with chlorine (Cl2), bromine (Br2), and iodine monochloride (ICI) are sensitive to the alkyl substituents, and the positions and number of vinyl fluorine atoms. These perturbations influence the symmetry of the halonium ion intermediates, which can be determined by the distribution of the Markovnikov to anti-Markovnikov products. A vinyl fluorine on the number-2 carbon favors an unsymmetrical intermediate with greater charge on the number-2 carbon unless the alkyl group is electron withdrawing. A vinyl fluorine on the terminal number-1 carbon favors positive charge development on that carbon unless a resonance stabilizing group is on the number-2 carbon. The symmetry of halonium ions with vinyl fluorines on both carbons-1 and -2 depends primarily on the characteristics of the alkyl substituent. Intermediates range from openions with the positive charge on carbon-2, to various bridged species, to open-ions on the terminal carbon.