202267-29-6

Basic information

• Product Name: 3(S)-amino-1-(4-nitro)phenylpyrrolidine
• Synonyms: 3(S)-amino-1-(4-nitro)phenylpyrrolidine
• CAS NO: 202267-29-6
• Molecular Weight: 207.232
• Mol File: 202267-29-6.mol

Chemical Properties

• CAS DataBase Reference: 3(S)-amino-1-(4-nitro)phenylpyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3(S)-amino-1-(4-nitro)phenylpyrrolidine(202267-29-6)
• EPA Substance Registry System: 3(S)-amino-1-(4-nitro)phenylpyrrolidine(202267-29-6)

Safety Data

• Hazardous Substances Data: 202267-29-6(Hazardous Substances Data)

Upstream product

• 202267-28-5 1-(4-nitro)phenyl-3(S)-trifluoroacetylaminopyrrolidine 
• 862686-31-5 tert-butyl [(3S)-(4-nitrophenyl)pyrrolidin-3-yl]carbamate 
• 350-46-9 4-Fluoronitrobenzene 

Downstream Products

• 1291057-78-7 1-benzo[b]thiophen-3-yl-3-[1-(4-nitrophenyl)-(S)-pyrrolidin-3-ylamino]propan-1-one 

Relevant articles and documents

Novel benzo[ b ]thiophene derivatives as new potential antidepressants with rapid onset of action

We report benzo[b]thiophene derivatives synthesized according to a dual strategy. 8j, 9c, and 9e with affinity values toward 5-HT7R and 5-HTT were selected to probe their antidepressant activity in vivo using the forced swimming text (FST). The results showed significant antidepressant activity after chronic treatment. 9c was effective in reducing the immobility time in FST even after acute treatment. These findings identify these compounds as a new class of antidepressants with a rapid onset of action.

Methods of treating insulin resistance syndrome and diabetes

This invention is directed to methods of treating insulin resistance syndrome and diabetes in a patient in need thereof, comprising administering to said patient a pharmaceutically effective amount of a compound derived from adenosine and analogues thereof, or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable prodrug thereof, an N-oxide thereof, a hydrate thereof or a solvate thereof, or a pharmaceutical composition comprising such compound.

Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties

A compound of the formula wherein K is N; Q is CH2or O; R6is hydrogen, alkyl, allyl, 2-methylallyl, 2-butenyl, or cycloalkyl where the nitrogen of the ring of X is substituted by Y; E is O or S; Y is hydrogen, alkyl, aralkyl, substituted aralkyl, aryl, substituted aryl, heterocyclyl, substituted heterocyclyl, heterocyclylalkyl, or substituted heterocyclylalkyl; and n and p are independently 0, 1, 2, or 3, provided that n+p is at least 1; T is hydrogen, alkyl, alkylcarbonyl, alkylthiocarbonyl, halo, carboxyl, A and B are independently hydrogen, alkyl, hydroxyalkyl, alkoxyalkyl, or OR′; or a pharmaceutically acceptable salt thereof, a pharmaceutic-ally acceptable prodrug thereof, an N-oxide thereof, a hydrate thereof or a solvate thereof.