202268-20-0

Upstream product

• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 159801-08-8 methyl (3R)-4-(tert-butyldiphenylsilyloxy)-3-hydroxybutanoate 

Downstream Products

• 202268-21-1 (R)-6-(tert-Butyl-diphenyl-silanyloxy)-5-hydroxy-hex-1-en-3-one 
• 1527512-87-3 (R)-2-(tert-butyldiphenylsilyloxy)-6-methyl-2H-pyran-4(3H)-one 
• 1527512-84-0 (R)-7-(tert-butyldiphenylsilyloxy)-6-hydroxyhept-1-en-4-one 
• 168777-40-0 [(2R,3R,5R)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-hydroxy-tetrahydro-furan-2-yl]-acetaldehyde 
• 152518-69-9 (2R,4R)-1-(tert-Butyl-diphenyl-silanyloxy)-hex-5-ene-2,4-diol 
• 168777-41-1 (2R,3R,5R)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-2-((E)-5-trimethylsilanyl-pent-2-en-4-ynyl)-tetrahydro-furan-3-ol 
• 168777-42-2 Acetic acid (2R,3R,5R)-5-(tert-butyl-diphenyl-silanyloxymethyl)-2-((E)-5-trimethylsilanyl-pent-2-en-4-ynyl)-tetrahydro-furan-3-yl ester 
• 168777-39-7 (3aR,5R,6aR)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-tetrahydro-furo[3,2-b]furan-2-one 

Relevant academic research and scientific papers

Concise total synthesis of (-)-erinapyrone b from d-(+)-malic acid

A convenient and facile enantioselective synthesis of (-)-erinapyrone B from commercially available D-(+)-malic acid has been achieved in seven steps. One of the key steps in this synthesis was the one-pot reaction of palladium(II)-mediated Wacker-type oxidative cyclization in the presence of a catalytic amount of p-toluenesulphonic acid (p-TsOH) which has been found to be effective for the preparation of enantiopure 2,3-dihydro-4H-pyran-4-one from the corresponding enantiopure β-hydroxyenone via enantio-enriched diketohydroxy intermediate.