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N3-CarboxyMethyl LuMiflavin, also known as Lumiflavin-3-acetic Acid, is a derivative of Lumiflavin (L473900) that possesses unique chemical properties. It is characterized by the presence of a carboxylic acid group attached to the N3 position of the Lumiflavin molecule, which allows for further functionalization and interaction with other molecules. This modification enhances its potential applications in various fields, particularly in the study of flavoproteins and riboflavin-binding protein interactions.

20227-26-3

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20227-26-3 Usage

Uses

Used in Photochemical Induced Dynamic Nuclear Polarization (photo-CIDNP) Studies:
N3-CarboxyMethyl LuMiflavin is used as a probe in photo-CIDNP studies for investigating the structure and function of flavoproteins. The acetic acid derivative of Lumiflavin enables researchers to gain insights into the electron transfer processes and the role of flavoproteins in various biological systems.
Used in Riboflavin-Binding Protein Interaction Studies:
N3-CarboxyMethyl LuMiflavin is employed as a tool in the study of riboflavin-binding protein interactions. The carboxylic acid group in the molecule allows for specific interactions with riboflavin-binding proteins, providing valuable information on the binding mechanisms and the role of these proteins in cellular processes.

Check Digit Verification of cas no

The CAS Registry Mumber 20227-26-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,2,2 and 7 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 20227-26:
(7*2)+(6*0)+(5*2)+(4*2)+(3*7)+(2*2)+(1*6)=63
63 % 10 = 3
So 20227-26-3 is a valid CAS Registry Number.

20227-26-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(7,8,10-trimethyl-2,4-dioxobenzo[g]pteridin-3-yl)acetic acid

1.2 Other means of identification

Product number -
Other names N3-Carboxymethyl Lumiflavin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:20227-26-3 SDS

20227-26-3Relevant academic research and scientific papers

PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER CONTAINING PLK1 INHIBITOR AS ACTIVE INGREDIENT

-

, (2022/02/11)

The present invention relates to a pharmaceutical composition for preventing, treating or alleviating cancer, containing a PLK1 inhibitor as an active ingredient, and a compound according to the present invention selectively binds to PBD of PLK1, thereby having advantages of high selectivity and binding affinity for PLK1 and low toxicity. Therefore, a PLK inhibitor compound according to the present invention can be effectively used as an anticancer agent by inhibiting the growth of various cancer cells, and can be expected to exhibit synergistic effects with existing developed anticancer agents through co-administration, in addition to individual administration thereof.

Synthesis and characterization of flavin-tethered peptide nucleic acid

Ikeda, Hisafumi,Yoshida, Kohzo,Ozeki, Makoto,Saito, Isao

, p. 2529 - 2531 (2007/10/03)

We synthesized flavin-containing PNA monomer unit 5 from lumiflavin and prepared PNAs containing a flavin moiety (FPNA) by the standard tBoc chemistry. Each PNA oligomer was purified by reversed-phase HPLC and characterized by MALDI-TOF MS and UV spectra. Thermodynamic analyses indicated that the PNA oligomer containing a flavin moiety near the amino terminal considerably stabilized the PNA-DNA hybrids.

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