340259-04-3Relevant academic research and scientific papers
NOVEL FUNCTIONAL PEPTIDE NUCLEIC ACID MONOMER AND PROCESS FOR PRODUCING THE SAME
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Page/Page column 14-15; 20, (2008/06/13)
A compound represented by general formula (I) below; (in the formula, A denotes B denotes R denotes H, NO2, NH2, NHCbz, Br, F, Cl or SO3Na2, and n is an integer of 1 to 4), and a process for producing the above
Synthesis and characterization of flavin-tethered peptide nucleic acid
Ikeda, Hisafumi,Yoshida, Kohzo,Ozeki, Makoto,Saito, Isao
, p. 2529 - 2531 (2007/10/03)
We synthesized flavin-containing PNA monomer unit 5 from lumiflavin and prepared PNAs containing a flavin moiety (FPNA) by the standard tBoc chemistry. Each PNA oligomer was purified by reversed-phase HPLC and characterized by MALDI-TOF MS and UV spectra. Thermodynamic analyses indicated that the PNA oligomer containing a flavin moiety near the amino terminal considerably stabilized the PNA-DNA hybrids.
