202272-32-0

Basic information

• Product Name: (L)-5’-O-(t-butyldiphenylsilyl)-2’,3-dideoxy-2’-fluoro-5-fluorocytidine
• Synonyms: (L)-5’-O-(t-butyldiphenylsilyl)-2’,3-dideoxy-2’-fluoro-5-fluorocytidine
• CAS NO: 202272-32-0
• Molecular Weight: 485.606
• Mol File: 202272-32-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (L)-5’-O-(t-butyldiphenylsilyl)-2’,3-dideoxy-2’-fluoro-5-fluorocytidine(CAS DataBase Reference)
• NIST Chemistry Reference: (L)-5’-O-(t-butyldiphenylsilyl)-2’,3-dideoxy-2’-fluoro-5-fluorocytidine(202272-32-0)
• EPA Substance Registry System: (L)-5’-O-(t-butyldiphenylsilyl)-2’,3-dideoxy-2’-fluoro-5-fluorocytidine(202272-32-0)

Safety Data

• Hazardous Substances Data: 202272-32-0(Hazardous Substances Data)

Upstream product

• 111878-21-8 2-trimethylsilyloxy-4-trimethylsilylamino-5-fluoropyrimidine 
• 2022-85-7 Flucytosine 
• 202272-29-5 1-O-acetyl-5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-2-fluoro-(L)-erythron-pentofuranose 
• 202272-27-3 (2S,4R)-5-(t-butyldiphenylsiloxy)-2-fluoropentan-4-olide 
• 202272-28-4 5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-2-fluoro-(L)-erythron-pentofuranose 
• 128075-94-5 (R)-5-{[(tert-butyldiphenylsilyl)oxy]methyl}dihydrofuran-2(3H)-one 

Relevant articles and documents

2′-fluoronucleosides

2′-Fluoro-nucleoside compounds are disclosed which are useful in the treatment of hepatitis B infection, hepatitis C infection, HIV and abnormal cellular proliferation, including tumors and cancer. The compounds have the general formulae: wherein Base is a purine or pyrimidine base;R1 is OH, H, OR3, N3, CN, halogen, CF3, lower alkyl, amino, loweralkylamino, di(lower)alkylamino, or alkoxy;R2 is H, phosphate, or a stabilized phosphate prodrug; acyl, or other pharmaceutically acceptable leaving benzyl, a lipid, an amino acid, peptide, or cholesterol; andR3 is acyl, alkyl, phosphate, or other pharmaceutically acceptable leaving group; or a pharmaceutically acceptable salt thereof.