202286-41-7

Basic information

• Product Name: N-(benzotriazol-1-ylmethyl)-α-(methylthio)phenylimine
• Synonyms: N-(benzotriazol-1-ylmethyl)-α-(methylthio)phenylimine
• CAS NO: 202286-41-7
• Molecular Weight: 282.369
• Mol File: 202286-41-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(benzotriazol-1-ylmethyl)-α-(methylthio)phenylimine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(benzotriazol-1-ylmethyl)-α-(methylthio)phenylimine(202286-41-7)
• EPA Substance Registry System: N-(benzotriazol-1-ylmethyl)-α-(methylthio)phenylimine(202286-41-7)

Safety Data

• Hazardous Substances Data: 202286-41-7(Hazardous Substances Data)

Upstream product

• 117067-55-7 N-(benzotriazol-1-ylmethyl)thiobenzoamide 
• 74-88-4 methyl iodide 

Downstream Products

• 80224-46-0 4-methyl-2-phenyl-1H-pyrrole-3-carbonitrile 
• 82221-51-0 1,2-diphenyl-5-(4-methylphenyl)imidazole 
• 59009-61-9 methyl 2,4-diphenylpyrrole-3-carboxylate 
• 63324-78-7 ethyl 2,4-diphenyl-1H-pyrrole-3-carboxylate 
• 173469-03-9 2-phenyl-3-(pyridin-4-yl)pyrrole 
• 173469-07-3 4-(benzotriazol-1-yl)-1,2-diphenyl-5-(4-methylphenyl)-4,5-dihydroimidazole 
• 52179-70-1 2-phenyl-1H-pyrrole-3-carbonitrile 
• 58443-28-0 (2,4-diphenyl-1H-pyrrol-3-yl)(phenyl)methanone 
• 148403-22-9 4-acetyl-2-phenylpyrrole 
• 69640-27-3 dimethyl 2-phenyl-1H-pyrrole-3,4-dicarboxylate 

Relevant articles and documents

Novel and convenient routes to substituted pyrroles and imidazoles

S-Methyl N-(benzotriazol-1-ylmethyl)thioimidate 6 is obtained by lithiation of the corresponding N-(benzotriazol-1-ylmethyl)thioamide 5 and subsequent reaction with methyl iodide. Derivative 6 undergoes [2+3] cycloaddition reactions with α,β-unsaturated -esters, -ketones and -nitriles, and vinylpyridines which are followed by elimination of benzotriazole and the thioalkoxy group, to give 2,3,4-trisubstituted pyrroles. Lithiation of 6 followed by reactions with imines gives cyclized 4,5-dihydroimidazoles 14 which upon further treatment with ZnBr2 or direct refluxing in toluene yield the 1,2,5-trisubstituted imidazoles 15 in good yields.