202331-75-7Relevant academic research and scientific papers
Transition metal mediated selective C vs N arylation of 2-aminonaphthoquinone and its application toward the synthesis of benzocarbazoledione
Ashok, Polu,Ilangovan, Andivelu
supporting information, p. 438 - 441 (2018/01/03)
Selective C vs N-arylation of 2-aminonaphthoquinone was achieved using different transition metal salts and arylboronic acids. Mn(OAc)3·2H2O provided C-arylated product whereas NiCl2·6H2O and Cu(OAc)2
Synthesis and evaluation of Hsp90 inhibitors that contain the 1,4-naphthoquinone scaffold
Kyle Hadden,Hill, Stephanie A.,Davenport, Jason,Matts, Robert L.,Blagg, Brian S.J.
body text, p. 634 - 640 (2009/08/07)
High-throughput screening of a library of diverse molecules has identified the 1,4-naphthoquinone scaffold as a new class of Hsp90 inhibitors. The synthesis and evaluation of a rationally-designed series of analogues containing the naphthoquinone core sca
